Gain a foundational understanding of gastrointestinal physiology and how the GI system functions in health and disease. Gastrointestinal Physiology, a volume in the Mosby Physiology Series, explains the fundamentals of this complex subject in a clear and concise manner, while helping you bridge the gap between normal function and disease with pathophysiology content throughout the book.
Helps you easily master the material in a systems-based curriculum with learning objectives, Clinical Concept boxes, highlighted key words and concepts, chapter summaries, self-study questions, and a comprehensive exam.
Keeps you current with recent advances in gastrointestinal physiology with coverage of the physiological significance of gastrointestinal peptides; the regulation of mucosal growth and cancer; details surrounding acid secretion and peptic ulcers; and more.
Includes clear, 2-color diagrams that simplify complex concepts.
Features clinical commentaries that show you how to apply what you've learned to real-life clinical situations.
Covers the regulation of pancreatic secretion and gallbladder contraction; the transport processes for the absorption of nutrients; facts about fat absorption; and the regulation of food intake.
Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
Complete the Mosby Physiology Series! Systems-based and portable, these titles are ideal for integrated programs.
Blaustein, Kao, & Matteson: Cellular Physiology and Neurophysiology
Cloutier: Respiratory Physiology
Koeppen & Stanton: Renal Physiology
Pappano & Weir: Cardiovascular Physiology
White, Harrison, & Mehlmann: Endocrine and Reproductive Physiology
Hudnall: Hematology: A Pathophysiologic Approach
Gain a foundational understanding of gastrointestinal physiology and how the GI system functions in health and disease. Gastrointestinal Physiology, a volume in the Mosby Physiology Series, explains the fundamentals of this complex subject in a clear and concise manner, while helping you bridge the gap between normal function and disease with pathophysiology content throughout the book.
Helps you easily master the material in a systems-based curriculum with learning objectives, Clinical Concept boxes, highlighted key words and concepts, chapter summaries, self-study questions, and a comprehensive exam.
Keeps you current with recent advances in gastrointestinal physiology with coverage of the physiological significance of gastrointestinal peptides; the regulation of mucosal growth and cancer; details surrounding acid secretion and peptic ulcers; and more.
Includes clear, 2-color diagrams that simplify complex concepts.
Features clinical commentaries that show you how to apply what you've learned to real-life clinical situations.
Covers the regulation of pancreatic secretion and gallbladder contraction; the transport processes for the absorption of nutrients; facts about fat absorption; and the regulation of food intake.
Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
Complete the Mosby Physiology Series! Systems-based and portable, these titles are ideal for integrated programs.
Blaustein, Kao, & Matteson: Cellular Physiology and Neurophysiology
Cloutier: Respiratory Physiology
Koeppen & Stanton: Renal Physiology
Pappano & Weir: Cardiovascular Physiology
White, Harrison, & Mehlmann: Endocrine and Reproductive Physiology
Hudnall: Hematology: A Pathophysiologic Approach
Chapter?1 Regulation: Peptides of the Gastrointestinal Tract
Objectives
General Characteristics
Discovery
Chemistry
Distribution and Release
Actions and Interactions
Candidate Hormones
Neurocrines
Paracrines
Clinical Applications
Clinical Tests
Summary
Key Words and Concepts
Chapter?2 Regulation: Nerves and Smooth Muscle
Objectives
Anatomy of the Autonomic Nervous System
Neurohumoral Regulation of Gastrointestinal Function
Anatomy of the Smooth Muscle Cell
Smooth Muscle Contraction
Summary
Key Words and Concepts
Chapter?3 Swallowing
Objectives
Chewing
Pharyngeal Phase
Esophageal Peristalsis
Receptive Relaxation of the Stomach
Clinical Applications
Clinical Tests
Summary
Key Words and Concepts
Chapter?4 Gastric Emptying
Objectives
Anatomic Considerations
Contractions of the Orad Region of the Stomach
Contractions of the Caudad Region of the Stomach
Contractions of the GastroduodenalJunction
Contractions of the Proximal Duodenum
Regulation of Gastric Emptying
Clinical Applications
Clinical Tests
Summary
Key Words and Concepts
Chapter?5 Motility of the Small Intestine
Objectives
Anatomic Considerations
Types of Contractions
Patterns of Contractions
Vomiting
Clinical Applications
Clinical Tests
Summary
Key Words and Concepts
Chapter?6 Motility of the Large Intestine
Objectives
Anatomic Considerations
Contractions of the Cecum and Ascending Colon
Contractions of the Descending and Sigmoid Colon
Motility of the Rectum and Anal Canal
Control of Motility
Clinical Significance
Clinical Tests
Summary
Key Words and Concepts
Chapter?7 Salivary Secretion
Objectives
Functions of Saliva
Anatomy and Innervation of the Salivary Glands
Composition of Saliva
Regulation of Salivary Secretion
Clinical Correlation
Summary
Key Words and Concepts
Chapter?8 Gastric Secretion
Objectives
Functional Anatomy
Secretion of Acid
Origin of the Electrical Potential Difference
Electrolytes of Gastric Juice
Stimulants of Acid Secretion
Stimulation of Acid Secretion
Inhibition of Acid Secretion
Pepsin
Mucus
Intrinsic Factor
Growth of the Mucosa
Clinical Applications
Summary
Key Words and Concepts
Chapter?9 Pancreatic Secretion
Objectives
Functional Anatomy
Mechanisms of Fluid and Electrolyte Secretion
Mechanisms of Enzyme Secretion
Regulation of Secretion
Cellular Basis for Potentiation
Response to a Meal
Clinical Applications
Summary
Key Words and Concepts
Chapter?10 Bile Secretion and Gallbladder Function
Objectives
Overview of the Biliary System
Constituents of Bile
Bile Secretion
Gallbladder Function
Expulsion of Bile
Clinical Applications
Clinical Tests
Summary
Key Words and Concepts
Chapter?11 Digestion and Absorption OF?NUTRIENTS
Objectives
Structural-Functional Associations
Digestion
Absorption
Adaptation of Digestive and Absorptive Processes
Carbohydrate Assimilation
Protein Assimilation
Lipid Assimilation
Vitamins
Summary
Key Words and Concepts
Chapter?12 Fluid and Electrolyte Absorption
Objectives
Bidirectional Fluid FluX
Ionic Content of Luminal Fluid
Transport Routes and Processes
Mechanism for Water Absorption and Secretion
Intestinal Secretion
Clinical Applications
Calcium Absorption
Iron Absorption
Summary
Key Words and Concepts
Chapter?13 Regulation of Food Intake
Objectives
Appetite Control
The Nervous System
The Endocrine System
The Gastrointestinal System
Clinical Applications
Summary
Key Words and Concepts
Appendix A Answer to Self-Study Problems
Appendix B Comprehensive Multiple-Choice Review Examination
Index
Leonard R. Johnson received a Ph.D. in physiology from the University of Michigan and then trained with Dr. Morton I. Grossman at UCLA. He spent 17 years as a Professor of Physiology at the University of Texas Medical School in Houston before moving to the University of Tennessee Health Science Center as the Thomas A. Gerwin Professor and Chairman of the Department of Physiology. He is the author or coauthor of over 250 papers on gastrointestinal physiology and holds an NIH MERIT Award. Currently he is the Vice Chancellor for Research at Tennessee.
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