Written by an interdisciplinary team of chemists, biologists and engineers from one of the leading European centers for microsystem research, MIC in Lyngby, Denmark, this book introduces and discusses the different aspects of (bio)chemical microsystem development. Unlike other, far more voluminous and theoretical books on this topic, this is a concise, practical handbook, dealing with analytical applications, particularly in the life sciences. Topics include: * microfluidics * silicon micromachining * glass and polymer micromachining * packaging * analytical chemistry illustrated with examples taken mainly from ongoing research projects at MIC.
Written by an interdisciplinary team of chemists, biologists and engineers from one of the leading European centers for microsystem research, MIC in Lyngby, Denmark, this book introduces and discusses the different aspects of (bio)chemical microsystem development. Unlike other, far more voluminous and theoretical books on this topic, this is a concise, practical handbook, dealing with analytical applications, particularly in the life sciences. Topics include: * microfluidics * silicon micromachining * glass and polymer micromachining * packaging * analytical chemistry illustrated with examples taken mainly from ongoing research projects at MIC.
Preface. 1. Introduction (Pieter Telleman). 2. Clean Rooms (Daria Petersen and Pieter Telleman). 3. Microfluidics - Theoretical Aspects (Jorg P. Kutter and Henning Klank). 4. Microfluidics - Components (Jorg Kutter, Klaus Bo Mogensen, Henning Klank, and Oliver Geschke). 5. Simulations in Microfluidics (Goran Goranovic and Henrik Bruus). 6. Silicon and Cleanroom Processing (Anders Michael Jorgensen and Klaus Bo Mogensen). 7. Glass Micromachining (Daria Petersen, Klaus Bo Mogensen, and Henning Klank). 8. Polymer Micromachining (Henning Klank). 9. Packaging of Microsystems (Gerardo Perozziello). 10. Analytical Chemistry on Microsystems (Jo P. Kutter and Oliver Geschke). Subject Index.
Oliver Geschke graduated in Chemistry in 1994 at the university of Munster, Germany. He joined the Institute for Chemical and Biochemical Sensor Research, Munster, Germany, where he carried out his PhD research titles "Development and Characterization of muTAS sensors analyzing phenolic compounds and dissolved oxygen - Ways to a laboratory on a chip". In December 1998 he joined the MIC at the Technical University of Denmark (DTU), kgs. Lyngby, Denmark, where he worked as an assistant professor on a European Project on wastewater analysers. In November 2001 he became Associated Professor at MIC where he is heading a research group "Polymeric Environmental Microsystems, POEM". Oliver has been supervising and co-supervising a number of MSc and PhD students and postdoctoral researchers. He published about 15 papers in various journals and international conference proceedings, contributed to two textbooks and holds one patent. Apart from his teaching duties at DTU he taught in several national and international courses - mostly on matter that is covered in this book. Henning Klank studied Physics at the Ludwig-Maximillian University in Munich, Germany, finishing with a MSc degree in experimental physics. The following years he spent at Massey University in Palmerston North, New Zealand, where he completed a PhD in Physics, working on the instrumentation for a scanning tunneling microscope. Currently Henning is working as a postdoctoral fellow at the um;TAS group at MIC at the Technical University of Denmark (DTU), kgs. Lyngby, Denmark. His general field of interest is instrumentation, automation and measurement. His most recent work at MIC involved fabrication of plastic Microsystems using infrared laser machining, particle image velocimetry and designing electronic measurement and processing equipment for Bio/Chemical MicroSystem. Pieter Telleman received a Chemical Engineering degree from the University of Twente, Enschede, The Netherlands, in 1987 and a MSc degree in Biochemistry from the University of Nijmegen, The Netherlands in 1990. In 1995 he received his PhD in Medicine from the University of Amsterdam (Amsterdam, The Netherland). In 1995 Pieter joined the Harvard University, Boston, MA, USA as a postdoctoral fellow at the Harvard Institutes of Medicine (HIM) followed by a postdoctoral fellowship at the Harvard Medical School (HMS), He joined the MIC at the Technical University of Denmark (DTU), kgs. Lyngby, Denmark, as a group leader of the Bio/Chemical MicroSystem group in 1998. Pieter was appointed Professor in Bio/Chemical MicroSystem at the DTU on July 1, 2001 and assumed the position of center director at MIC in 2003. His research focuses on the application of micro- and nanotechnology to chemistry and the life sciences where the aim is to perform complete chemical and bio/chemical analyses on silicon, glass and plastic chips thereby improving overall performance.
"Insgesamt ist das Buch eine nutzliche Erganzung der auf dem Markt befindlichen einschlagigen Literatur und kann als Lehrbuch fur das Grundstudium oder als Einfuhrung in die Mikrofluidik dienen." Jaisree Moorthy, David T. Eddington, David J. Beebe, University of Wisconsin, Madison (USA) Angewandte Chemie 2004-116/34 "Uber den Bereich Lab-on-a-Chip gibt es schon das ein oder andere editierte Buch. Das hier zu diskutierende Werk ist aber nicht nur aktueller, es bietet dem Leser auch mehr. ... Das Buch bietet profunde und logisch dargelegte Information und liest sich dabei leicht. Man merkt , dass hier "Uberzeugungstater" schreiben; die Begeisterung fur das Thema schwingt immer wieder durch. Das Buch wird auch seinem Titel und damit Anspruch gerecht. Der Leser wird bestens uber die Ingenieuraspekte zu Lab-on-a-Chip informiert." Volker Hessel, Mainz, Chemie Ingenieur Technik, 11/2004 "Jetzt liegt auch eine uberschaubare, praxistaugliche Einfuhrung vor, die nicht das gesamte Gebiet der Mikroreaktoren und mikromechanischen Systeme abdecken will, sondern sich auf analytische Anwendungen in der Chemie und den Lebenswissenschaften konzentriert." BIO WORLD
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