Table of Contents

Processes of Drug Handling by the Body. The Design of Drug Delivery Systems. Intermolecular Forces and Molecular Modeling. Drug Chirality and its Pharmacological Consequences. Quantitative Structure-Activity Relationships and Drug Design. From Program Sanction to Clinical Trials: A Partial View of the Quest for Arimidex , a Potent, Selective Inhibitor of Aromatase. Pro-Drugs. Design of Enzyme Inhibitors as Drugs. The Chemotherapy of Cancer. Neurotransmitters, Agonists and Antagonists. Design of Antimicrobial Chemotherapeutic Agents. Recombinant DNA technology: Monoclonal Antibodies. Bio-inorganic Chemistry and its Pharmaceutical Applications.